Drug Development Failure: How GLP-1 Development Was Abandoned in 1990
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Researchers at Eli Lilly and Company began developing a medication based on the glucagon-like peptide-1 (GLP-1) hormone in the 1980s. The goal was to create a treatment for type 2 diabetes. However, the project was abandoned in 1990 due to concerns about the medication's potential side effects. This setback delayed the development of GLP-1-based treatments, which are now used to manage diabetes and obesity.
This story highlights the challenges and setbacks that can occur in pharmaceutical development, and how they can impact the availability of treatments for patients.
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Score: 1 on Hacker News
- ▸01GLP-1 is a hormone involved in glucose metabolism and appetite regulation.
- ▸02Eli Lilly and Company initiated GLP-1-based medication development in the 1980s.
- ▸03The project was abandoned in 1990 due to potential side effects.
- ▸04GLP-1-based treatments are now used to manage diabetes and obesity.
Drug Development Failure: How GLP-1 Development Was Abandoned in 1990. Score: 1 on Hacker News
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